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Product Name: Sodium Saccharin Anhydrous Powder E954 Model NO.: food grade Resource: Chemosynthesis Effect: Sweetener Nutritional Value: Non-nutritional Type Type: Saccharin Sodium EINECS: 204-886-1 Formula: C7h4o3ns CAS No.: 128-44-9 Store: Dry and Cool Place M G: 206.17 Packing: 25kg/Bag Packing 2: 25kg/Drum Packing 3: 25kg/Carton Trademark: JK Transport Package: 25kg/Bag, 25kg/Carton Specification: BP/USP/FCC Origin: China HS Code: 292511 Product Description Uses:1. In the medicine field, it can keep the balance of acid and alkali in the human body, and recover the normal operation of nerve. It can be used in the preventation and cure of syndrome for low sodium. In this purpose, it also can Be used as food additives.2. It can be used as water quality stabilizer because it has excellent inhibiting capacity to scale.3. Used as surface cleaning agent of metal4. Used as cleaning agent of glass bottle5. It also can be used as water reducing agent and retarderITEMS STANDARDIdentificationPositiveMelting point of insolated saccharinºC226-230ºCAppearanceWhite crystalsContent %≥98.5%IdentityComplies with BP/USPLoss on drying %≤0.3%Arsenic ppm≤3ppmBenzoate and salicylateNo precipitate or violet color appearsHeavy metals ppm≤10ppmFree acid or alkaliComplies with BP /USPReadily carbonizable substancesNot more intensely colored than referenceP-toluene sulfonamide≤10ppmO-toluene sulfonamide≤10ppmSelenium ppm≤30ppmRelated substanceComplies with DABSulfated AshesComplies with BP/USPOrganic volatilesComplies with BPZinc ppm≤30ppmSaccharin sodium Basic informationDescription ReferencesProduct Name:Saccharin sodiumSynonyms:Sodium 1,1-dioxo-1,2-benzothiazol-2-id-3-one;2-Sodio-1,2-benzisothiazol-3(2H)-one 1,1-dioxide;o-Benzoic acid sulfimide sodium;o-Benzoic Sulfimide Sodium Salt Saccharin Sodium Salt;o-SulfobenziMide SodiuM Salt ;benzo[d]isothiazol-3(2H)-one 1,1-dioxide, sodiuM salt;Sodium 3-oxo-3H-benzo[d]isothiazol-2-ide 1,1-dioxide;o-SulfobenziMide SodiuM Salt Dihydrate, 98.0%,(LC&TCAS:128-44-9MF:C7H5NNaO3SMW:206.17EINECS:204-886-1Product Categories:Food additives;Food addivite, Sweeteners;Food additive, Sweeteners;Food and Feed Additive;Classes of metal Compounds;Na (Sodium) Compounds (excluding simple sodium salts);Typical metal CompoundsMol File:128-44-9.molSaccharin sodium Chemical PropertiesMelting point>300°CFEMA2997 |SACCHARINE, SODIUM SALTstorage temp.0-6°CsolubilityH2O: 1M at 20 °C, clear, colorlessformneatWater Solubility>=10 g/100 mL at 20 ºCStability:Stable. Incompatible with strong oxidizing agents.InChIKeyWINXNKPZLFISPD-UHFFFAOYSA-MCAS Database Reference128-44-9(CAS Database Reference)EPA Substance Registry SystemSaccharin sodium (128-44-9)Safety InformationSafety Statements24/25WGK Germany2RTECSDE4550000ToxicityLD50 oral in rat: 14200mg/kgMSDS InformationProviderLanguageSodium 1,2-benzisothiasolin-3-one-1,1-dioxideEnglishSigmaAldrichEnglishACROSEnglishSaccharin sodium Usage And SynthesisDescriptionSaccharin sodium is atype of artificial or nonnutritive sweetener. It is 200 to 700 times sweeter than sucrose but has abitter aftertaste. Saccharin and its salts do not occur naturally. Saccharin sodium is used in the production of various foods and pharmaceutical products including soft drinks, candy, biscuits, jams, chewing gum, tinned fruit, medicine and toothpaste.References[1] DeeAn Jones, Environmental Fate of Cypermethrin[2] http://www.inchem.org[3] http://npic.orst.eduChemical PropertiesSaccharine sodium salt has no odor, but has an intensly sweet taste.Chemical Propertieswhite powderChemical PropertiesSaccharin is acrystalline solid with asweet taste (500 times sweeter than sugar).Chemical PropertiesSaccharin sodium occurs as awhite, odorless or faintly aromatic, efflorescent, crystalline powder. It has an intensely sweet taste, with ametallic or bitter aftertaste that at normal levels of use can be detected by approximately 25% of the population. The aftertaste can be masked by blending saccharin sodium with other sweeteners. Saccharin sodium can contain variable amounts of water.UsesSweetener (non-nutritive).Production MethodsSaccharin is produced by the oxidation of o-toluene sulfonamide by potassium permanganate in asolution of sodium hydroxide. Acidification of the solution precipitates saccharin, which is then dissolved in water at 50ºC and neutralized by addition of sodium hydroxide. Rapid cooling of the solution initiates crystallization of saccharin sodium from the liquors.Brand nameSucaryl (Ross).General DescriptionOdorless white crystals or crystalline powder. Aqueous solution is neutral or alkaline to litmus, but not alkaline to phenolphthalein. Effloresces in dry air. Intensely sweet taste.Air &Water ReactionsWater soluble.Reactivity ProfileSaccharin sodium may react with oxidizing agents. .Very weak base in aqueous solution.HazardThe use of saccharin is being limited due to possible carcinogenicity.Fire HazardFlash point data are not available for Saccharin sodium ,but Saccharin sodium is probably combustible.Pharmaceutical ApplicationsSaccharin sodium is an intense sweetening agent used in beverages, food products, table-top sweeteners, and pharmaceutical formulations such as tablets, powders, medicated confectionery, gels, suspensions, liquids, and mouthwashes. It is also used in vitamin preparations.Saccharin sodium is considerably more soluble in water than saccharin, and is more frequently used in pharmaceutical formulations. Its sweetening power is approximately 300-600 times that of sucrose. Saccharin sodium enhances flavor systems and may be used to mask some unpleasant taste characteristics.Injection of saccharin sodium has been used to measure the armto- tongue circulation time.Safety ProfileConfirmed carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by ingestion and intraperitoneal routes. Apromoter. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx, Na2O, and NOx.SafetyThere has been considerable controversy concerning the safety of saccharin and saccharin sodium in recent years; however, it is now generally regarded as asafe, intense sweetener. See Saccharin for further information.The WHO has set atemporary acceptable daily intake of up to 2.5 mg/kg body-weight for saccharin, including its salts.(3) In the UK, the Committee on Toxicity of Chemicals in Food, Consumer Products, and the Environment (COT) has set an acceptable daily intake for saccharin and its salts (expressed as saccharin sodium) at up to 5mg/kg body-weight.LD50 (mouse, oral): 17.5 g/kgLD50 (rat, IP): 7.1 g/kgLD50 (rat, oral): 14.2 g/kgPotential ExposureThe information provided has to do, primarily, with the manufacturing of saccharin. Saccharin has been used as anonnutritive sweetening agent. At one point the United States consumption pattern for all forms of saccharin has been estimated as 45% in soft drinks; 18% in tabletop sweeteners; 14% in fruits, juices, sweets, chew- ing gum, and jellies; 10% in cosmetics and oral hygiene products; 7% in drugs, such as coating on pills; 2% in tobacco; 2% in electroplating; and 2% for miscellaneous uses. Human exposure to saccharin occurs primarily through ingestion because of its use in many dietic foods and drinks and some personal hygiene products, including toothpastes and mouthwashes. The general public is exposed to saccharin, especially by persons required to reduce sugar intake.storageSaccharin sodium is stable under the normal range of conditions employed in formulations. only when it is exposed to ahigh temperature (125ºC) at alow pH (pH 2) for over 1hour does significant decomposition occur. The 84% grade is the most stable form of saccharin sodium since the 76% form will dry further under ambient conditions. Solutions for injection can be sterilized by autoclave.Saccharin sodium should be stored in awell-closed container in adry place.ShippingUN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz- ardous material, Technical Name Required.IncompatibilitiesSaccharin sodium does not undergo Maillard browning.IncompatibilitiesDust may form explosive mixture with air. Incompatible with strong oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, and epoxides.Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contami- nant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal.Regulatory StatusAccepted for use as afood additive in Europe; 'E954' is applied to both saccharin and saccharin salts. Included in the FDA Inactive Ingredients Database (buccal and dental preparations; IM and IV injections; oral and topical preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.Saccharin sodium Preparation Products And Raw materialsPreparation ProductsChlorimuron-ethyl-->Piroxicam